LncRNA MALAT1 regulates inflammatory cytokine production in lipopolysaccharide-stimulated human gingival fibroblasts through sponging miR-20a and activating TLR4 pathway.

Jiashan LiMinwei WangLiting SongXiangpu WangWen LaiShaoyun Jiang

Published in: Journal of periodontal research (2019)

MALAT1 enhances inflammatory cytokine production through sponging miR-20a and releasing TLR4, indicating a regulatory role of MALAT1 in periodontal inflammation.

Keyphrases

long non coding rna
toll like receptor
inflammatory response
long noncoding rna
oxidative stress
cell proliferation
endothelial cells
immune response
nuclear factor
lps induced
transcription factor
signaling pathway
induced pluripotent stem cells