Adipose Tissue-Derived Mesenchymal Stem Cells (ADMSCs) and ADMSC-Derived Secretome Expedited Wound Healing in a Rodent Model - A Preliminary Study.

Hui Ma Ping Kuen LamWing Sum SiuCindy See Wai TongKin Ki Yan LoChi Man KoonXiao Xiao WuXiang LiWen ChengWai Ting ShumPing Chung Leung

Published in: Clinical, cosmetic and investigational dermatology (2021)

Our study indicated both MSCs and MSCs-derived secretome enhanced the wound healing process in early phase. Secretome further promoted the healing effects through promoting the fibroblast proliferation and migration and suppressing the inflammatory response.

Keyphrases

wound healing
inflammatory response
adipose tissue
mesenchymal stem cells
umbilical cord
signaling pathway
lipopolysaccharide induced
lps induced
insulin resistance
high fat diet
type diabetes
metabolic syndrome
toll like receptor