Clinical surrogates of dysautonomia predict lethal outcome in COVID-19 on intensive care unit.
Marcel Seungsu WooChristina MayerMarlene FischerStefan KlugeKevin RoedlChristian GerloffPatrick CzorlichGötz ThomallaJulian Schulze Zur WieschNils SchweingruberPublished in: Neurological research and practice (2023)
Our study suggests autonomic dysfunction as a contributor to mortality in critically ill COVID-19 patients during the first waves of the pandemic. Serving as a surrogate for disease progression, these findings could contribute to the clinical management of COVID-19 patients admitted to the ICU. Furthermore, the suggested measure of dysautonomia and correlation with other laboratory parameters is non-invasive, simple, and cost-effective and should be evaluated as an additional outcome parameter in septic patients treated in the ICU in the future.
Keyphrases
- sars cov
- intensive care unit
- coronavirus disease
- mechanical ventilation
- respiratory syndrome coronavirus
- acute kidney injury
- oxidative stress
- heart rate variability
- risk factors
- current status
- cardiovascular disease
- coronary artery disease
- heart rate
- type diabetes
- cardiovascular events
- extracorporeal membrane oxygenation