Association of CSF proteins with tau and amyloid β levels in asymptomatic 70-year-olds.
Julia RemnestålSofia BergströmJennie OlofssonEvelina SjöstedtMathias UhlénKaj BlennowHenrik ZetterbergAnna ZettergrenSilke KernIngmar SkoogPeter NilssonAnna MånbergPublished in: Alzheimer's research & therapy (2021)
We identified a series of transmembrane proteins, proteins associated with or anchored to the plasma membrane, and proteins involved in or connected to synaptic vesicle transport to be associated with CSF biomarkers of amyloid and tau pathology in AD. Further studies are needed to explore these proteins' role in AD pathophysiology.
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