Characterization of the fragmentation mechanisms in electrospray ionization tandem mass spectrometry of chloroquinoline derivatives with larvicidal activity against Aedes aegypti.
Rodrigo Moreira da SilvaJéssica Guastalli BarbieriValter Eduardo MurieMaíra Rosato Silveira SilvérioRafael Augusto SoldiLorena Carneiro AlbernazLaila Salmen EspindolaPaulo Cézar VieiraGiuliano Cesar ClososkiRicardo VessecchiNorberto Peporine LopesPublished in: Rapid communications in mass spectrometry : RCM (2024)
Our results provided a well-founded characterization of the fragmentation reactions of DCQ and its derivatives, which can be useful for complementary studies of the development of a larvicidal product against Ae. aegypti.
Keyphrases
- aedes aegypti
- tandem mass spectrometry
- zika virus
- ultra high performance liquid chromatography
- dengue virus
- high performance liquid chromatography
- liquid chromatography
- gas chromatography
- simultaneous determination
- solid phase extraction
- mass spectrometry
- high resolution
- high resolution mass spectrometry
- structure activity relationship
- essential oil