Prevalent Metformin Use in Adults With Diabetes and the Incidence of Long COVID: An EHR-Based Cohort Study From the RECOVER Program.

Steven G JohnsonSajjad AbedianTil StürmerJared D HulingColby Lewis VJohn B BuseShari B BrosnahanPraveen C MudumbiKristine M ErlandsonGrace A McComseyJonathan ArnoldTalia D WiggenRachel WongShawn MurphyClifford RosenRainu KaushalMark G WeinerCarolyn Bramantenull null

Published in: Diabetes care (2024)

Prevalent metformin use is associated with a slightly lower incidence of death or PASC after SARS-CoV-2 infection. PASC incidence by computable phenotype is higher than by EHR code, especially in PCORnet. These data are consistent with other observational analyses showing prevalent metformin is associated with favorable outcomes after SARS-CoV-2 infection in adults with T2DM.

Keyphrases

electronic health record
risk factors
respiratory syndrome coronavirus
coronavirus disease
sars cov
type diabetes
glycemic control
quality improvement
adipose tissue
machine learning
skeletal muscle