Skeletal muscle quality predicts overall survival in advanced liver hepatocellular carcinoma treated with SIRT and sorafenib: A subanalysis of the SORAMIC trial.

Alexey SurovAndreas WienkeJan BorggrefeMattes HinnerichsRicarda SeidenstickerOsman ÖcalKerstin SchütteChristoph J ZechChristian LoeweOtto van DeldenVincent VandecaveyeChris VerslypeBernhard GebauerChristian SengelIrene BargelliniRoberto IezziPeter MalfertheinerThomas BergHeinz J KlümpenJulia BenckertAntonio GasbarriniHolger AmthauerBruno SangroJens RickeMax Seidensticker

Published in: United European gastroenterology journal (2024)

Associations between parameters of muscle quality and OS are different in accordance to the treatment strategy and etiology of HCC. These findings highlight the prognostic potential of skeletal muscle quality in patients with advanced HCC.

Keyphrases

skeletal muscle
insulin resistance
quality improvement
clinical trial
oxidative stress
study protocol
risk assessment
metabolic syndrome
human health
climate change
phase ii
ischemia reperfusion injury
combination therapy
newly diagnosed
open label
double blind