APLP2 is predominantly cleaved by β-secretase and γ-secretase in the human brain.
Kanta YanagidaRiki MaruyamaShinji TagamiTakashi KudoMasayasu OkochiAkio FukumoriPublished in: Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society (2023)
Thus, these findings may contribute to a better understanding of the role of APP family proteins in Alzheimer's disease.
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