Defining a therapeutic range for adalimumab serum concentrations in the management of pediatric noninfectious uveitis, a step towards personalized treatment.
Joke DehoorneHelena GrothEmma CarléIlse De SchrijverCeline SysPatricia DelbekeElke O KrepsThomas RensonCarolien BonroyPublished in: Pediatric rheumatology online journal (2023)
A therapeutic range of adalimumab trough levels of 9.6 to 13 µg/mL, which corresponds with an optimal clinical effect, was identified. Therapeutic drug monitoring may guide the optimisation of treatment efficacy in children with NIU in the treat-to-target era.