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Defining a therapeutic range for adalimumab serum concentrations in the management of pediatric noninfectious uveitis, a step towards personalized treatment.

Joke DehoorneHelena GrothEmma CarléIlse De SchrijverCeline SysPatricia DelbekeElke O KrepsThomas RensonCarolien Bonroy
Published in: Pediatric rheumatology online journal (2023)
A therapeutic range of adalimumab trough levels of 9.6 to 13 µg/mL, which corresponds with an optimal clinical effect, was identified. Therapeutic drug monitoring may guide the optimisation of treatment efficacy in children with NIU in the treat-to-target era.
Keyphrases
  • juvenile idiopathic arthritis
  • rheumatoid arthritis
  • young adults
  • combination therapy
  • disease activity