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Irbesartan ameliorates diabetic kidney injury in db/db mice by restoring circadian rhythm and cell cycle.

Hailing ZhaoZhiguo LiMeihua YanLiang MaXi DongXin LiHaojun ZhangPing Li
Published in: Journal of translational internal medicine (2024)
Generally, irbesartan can effectively treat DKD by regulating the circadian rhythm and cell cycle. The DEGs and pathways identified in the study will provide new insights into the potential mechanisms of irbesartan in the treatment of DKD.
Keyphrases
  • cell cycle
  • cell proliferation
  • atrial fibrillation
  • heart rate
  • type diabetes
  • high fat diet induced
  • blood pressure
  • wound healing
  • metabolic syndrome
  • combination therapy
  • risk assessment
  • smoking cessation