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Comparative transcriptomic analyses and single-cell RNA sequencing of the freshwater planarian Schmidtea mediterranea identify major cell types and pathway conservation.

Lakshmipuram Seshadri SwapnaAlyssa M MolinaroNicole Lindsay-MosherBret J PearsonJohn Parkinson
Published in: Genome biology (2018)
In general, S. mediterranea displays a high level of gene and pathway conservation compared with other model systems, rendering it a viable model to study the roles of these pathways in stem cell biology and regeneration.
Keyphrases
  • single cell
  • stem cells
  • rna seq
  • high throughput
  • cell therapy
  • genome wide
  • bone marrow