Autograft immune effector cells and survival in autologous peripheral blood hematopoietic stem cell transplantation.
Luis F PorrataPublished in: Journal of clinical apheresis (2017)
In addition to stem cells, T-cells, natural killer cells, dendritic cells, and monocytes are also collected and infused from the autograft in patients undergoing autologous peripheral blood hematopoietic stem cell transplantation. Recent reports have shown that these autograft immune effector cells can affect the clinical outcome postautologous peripheral blood hematopoietic stem cell transplantation. In this article, I will review the clinical impact on the survival of these autograft immune effector cells conferring the concept of autologous graft versus tumor effect.
Keyphrases
- peripheral blood
- dendritic cells
- induced apoptosis
- stem cells
- cell cycle arrest
- patients undergoing
- regulatory t cells
- acute myeloid leukemia
- bone marrow
- cell therapy
- immune response
- anterior cruciate ligament reconstruction
- endoplasmic reticulum stress
- natural killer cells
- emergency department
- type iii
- pi k akt
- cell proliferation
- free survival
- adverse drug