Multi-center retrospective study of the prognosis and treatment outcomes of Japanese oral squamous cell carcinoma patients with single lymph node metastasis and extra nodal extension.
Takumi HasegawaSouichi YanamotoMitsunobu OtsuruYasumasa KakeiMasaya OkuraNobuhiro YamakawaShin-Ichi YamadaYoshihide OtaMasahiro UmedaTadaaki KiritaHiroshi KuritaMichihiro UedaTakahide Komorinull nullPublished in: Journal of surgical oncology (2018)
The prognosis of ENE + pN1 was not as poor as that of ENE + MLM, although both these groups feature ENE. Adjuvant therapy (RT/CCRT) after surgery is recommend for cases of ENE + pN1.