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Characteristics of inflammatory response and repair after experimental blast lung injury in rats.

Jürg HamacherYalda HadizamaniHanno HuwerUeli MoehrlenLia BallyUz StammbergerAlbrecht WendelRudolf Lucas
Published in: PloS one (2023)
Using a stablished model, can facilitate the study of inflammatory response to blast lung injury. Following the blast injury, alteration in cytokine/chemokine profile and activity of cells in the alveolar space occurs, which eventuates in alveolar epithelial barrier dysfunction and oedema formation. Most of these parameters exhibit time-dependent return to their basal status that is an indication to resilience of lungs to blast-induced lung injury.
Keyphrases
  • inflammatory response
  • induced apoptosis
  • oxidative stress
  • cell cycle arrest
  • high glucose
  • lipopolysaccharide induced
  • endothelial cells
  • toll like receptor
  • endoplasmic reticulum stress