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Mechanism of Jujube ( Ziziphus jujuba Mill.) Fruit in the Appetite Regulation Based on Network Pharmacology and Molecular Docking Method.

Yu ZhuDan ZhongTao ShenRensong Yue
Published in: Contrast media & molecular imaging (2022)
Based on network pharmacology, the appetite modulating effects of jujube on multiple components, targets, and channels were explored, and the main active components of jujube were predicted to act on multiple signaling pathways to regulate appetite. The molecular docking results showed that the components in jujube had strong binding activity to the main targets, which provided new ideas and methods to further investigate the mechanisms of appetite regulation by jujube.
Keyphrases
  • molecular docking
  • weight loss
  • body weight
  • molecular dynamics simulations
  • signaling pathway
  • cell proliferation
  • induced apoptosis