Transmembrane 6 superfamily member 2 167K allele improves renal function in children with obesity.
Pierluigi MarzuilloAnna Di SessaGrazia CirilloGiuseppina Rosaria UmanoMarcella PedullàAngela La MannaStefano GuarinoEmanuele Miraglia Del GiudicePublished in: Pediatric research (2020)
Children with obesity carrying the TM6SF2 167K allele show higher eGFR levels compared with E167 allele homozygous subjects, independently of NAFLD. A major effect of this polymorphism in the presence of NAFLD was captured.