Tissue-dependent differences in Bardet-Biedl syndrome gene expression.

Sarita Rani PatnaikAalaa FaragLena BrückerAnn-Kathrin VolzSandra SchneiderViola KretschmerHelen Louise May-Simera

Published in: Biology of the cell (2020)

Our data support the hypothesis that in some organs, BBS proteins not only function in a complex but might also have alternative functions in a ciliary independent context. This significantly alters our understanding of disease pathogenesis and development of possible treatment strategies.

Keyphrases

gene expression
dna methylation
electronic health record
big data
case report
machine learning