Aspartate Alleviates Colonic Epithelial Damage by Regulating Intestinal Stem Cell Proliferation and Differentiation via Mitochondrial Dynamics.

Dan WangYanling KuangZhicheng WanPei LiJiangchao ZhaoHuiling ZhuYulan Liu

Published in: Molecular nutrition & food research (2022)

The findings indicate that aspartate promotes ISC proliferation and differentiation to alleviate colonic epithelial damage by regulation of mitochondrial metabolism and dynamics.

Keyphrases

oxidative stress
stem cells
signaling pathway
ulcerative colitis
mouse model