Associations Between Genomic Variants in Alcohol Dehydrogenase Genes and Alcohol Symptomatology in American Indians and European Americans: Distinctions and Convergence.

Qian PengIan R GizerKirk C WilhelmsenCindy L Ehlers

Published in: Alcoholism, clinical and experimental research (2017)

Our results suggest that ADH variants, both common and rare, are more likely to impact risk for alcohol-related symptomatology in this AI population than in this EA sample, and ADH variants that might affect AUD are likely different but convergent on similar regions between the 2 populations.

Keyphrases

copy number
alcohol consumption
genome wide
artificial intelligence
gene expression
transcription factor
deep learning
genome wide identification
drug induced