The epidemiology of epidermolysis bullosa in England and Wales: data from the national epidermolysis bullosa database.
Gabriela PetrofMaria PapanikolaouAnna E MartinezJemima E MellerioJohn A McGrathAjoy BardhanNatasha HarperAdrian HeagertyMalobi OgboliChristopher ChiswellCelia MossPublished in: The British journal of dermatology (2022)
In this study, we provide the first accurate epidemiological data for EB in England and Wales. We believe the observed reduction in birth incidence of severe types of EB reflects an uptake of genetic counselling advice, whereas the reduction in milder types may be due to delayed presentation. A potential small trend towards longer survival of babies with JEB-S may reflect improved multidisciplinary care.
Keyphrases
- quality improvement
- electronic health record
- risk factors
- big data
- healthcare
- gestational age
- palliative care
- high resolution
- machine learning
- data analysis
- risk assessment
- pain management
- artificial intelligence
- pregnant women
- deep learning
- free survival
- hepatitis c virus
- mass spectrometry
- hiv testing
- human immunodeficiency virus
- pregnancy outcomes