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Cytokine profiles in Tibetan macaques following α-1,3-galactosyltransferase-knockout pig liver xenotransplantation.

Zhuochao ZhangXiao LiHong ZhangXuan ZhangHui ChenDengke PanHongchen JiLiang ZhouJuan LingJingshi ZhouShuqiang YueDesheng WangZhaoxu YangKaishan TaoKefeng Dou
Published in: Xenotransplantation (2017)
Here, we established a modified auxiliary liver xenotransplantation model resulting in near-normal hepatic function. Inflammatory cytokines might contribute to early damage in liver xenografts. Controlling the systemic inflammatory response of recipients might prevent early post-Tx graft dysfunction.
Keyphrases
  • inflammatory response
  • oxidative stress
  • lipopolysaccharide induced
  • lps induced