Transcriptome Analysis Reveals Organ-Specific Effects of 2-Deoxyglucose Treatment in Healthy Mice.
Ann E WellsJohn J WilsonSarah E HeuerJohn D SearsJian WeiRaghav PandeyMauro W CostaDerry C RoopenianChih-Hao ChangGregory W CarterPublished in: bioRxiv : the preprint server for biology (2023)
These findings suggest that 2DG has a systemic impact that varies across organs, potentially affecting multiple pathways and functions. The study provides insights into the potential therapeutic benefits of 2DG across different diseases and highlights the importance of understanding its systemic effects for future research and clinical applications.