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Quantitative multiplex immunofluorescence analysis identifies infiltrating PD1+ CD8+ and CD8+ T cells as predictive of response to neoadjuvant chemotherapy in breast cancer.

Hongling LiangHongsheng LiZhi XieTianen JinYu ChenZhiyi LvXiaojun TanJia LiGuodong HanWeixing HeNi QiuMing JiangJie ZhouHaoming XiaYongtao ZhanLulu CuiWeiling GuoJianqing HuangXu Chao ZhangYi-Long Wu
Published in: Thoracic cancer (2020)
Incremental levels of PD1+ CD8+ T cells in non-pCR post-NAT tumors suggest PD1 inhibition might benefit in the neoadjuvant setting.
Keyphrases
  • neoadjuvant chemotherapy
  • locally advanced
  • lymph node
  • rectal cancer
  • sentinel lymph node
  • squamous cell carcinoma
  • genome wide
  • radiation therapy
  • gene expression
  • high throughput
  • dna methylation
  • young adults