A Case Report on Longitudinal Collection of Tumour Biopsies for Gene Expression-Based Tumour Microenvironment Analysis from Pancreatic Cancer Patients Treated with Endoscopic Ultrasound Guided Radiofrequency Ablation.

Patrick V LawrenceKrisha DesaiChristopher WadsworthNagina Mangal Hemant Mahendrakumar Kocher Nagy A Habib Anguraj SadanandamMikael H Sodergren

Published in: Current oncology (Toronto, Ont.) (2022)

This case study suggests longitudinal EUS-FNAB as a potential resource to study tumour and microenvironmental changes associated with RFA treatment. A large sample size is required in the future to assess the efficacy and safety of the treatment and perform comprehensive statistical analysis of EUS-RFA-based molecular changes in PDAC.

Keyphrases

radiofrequency ablation
ultrasound guided
gene expression
fine needle aspiration
stem cells
dna methylation
combination therapy
climate change
endoscopic submucosal dissection