Host immune responses induced by specific Mycobacterium leprae antigens in an overnight whole-blood assay correlate with the diagnosis of paucibacillary leprosy patients in China.

Xiaohua ChenYuan-Gang YouYou-Hua YuanLian C YuanYan Wen

Published in: PLoS neglected tropical diseases (2019)

Our findings suggest that the host markers induced by specific M. leprae antigens in an overnight WBA increase diagnostic and discriminatory value in PB patients with leprosy, with a particularly strong association with interleukin 8.

Keyphrases

immune response
end stage renal disease
dendritic cells
ejection fraction
newly diagnosed
chronic kidney disease
mycobacterium tuberculosis
prognostic factors
heavy metals
toll like receptor
single cell