Utilizing Mass Spectrometry to Detect and Isotype Monoclonal Proteins in Urine: Comparison to Electrophoretic Methods.

Danelle H MoonenMindy KohlhagenSurendra DasariMaria Alice Vieira WillrichTaxiarchis KourelisAngela DispenzieriDavid L Murray
Published in: Clinical chemistry (2023)
u-MASS-FIX is a reliable alternative to u-IFE with the added benefits of LC glycosylation detection and MP mass tracking between serum and urine. Furthermore, u-MASS-FIX is performed using neat urine. Eliminating the need to concentrate urine for u-IFE has potential to increase productivity by decreasing labor minutes per test.