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Molecular and cellular paradigms of multidrug resistance in cancer.

Foram U VaidyaAbu Sufiyan ChhipaVinita MishraVishal Kumar GuptaShiv Govind RawatAjay KumarChandramani Pathak
Published in: Cancer reports (Hoboken, N.J.) (2020)
MDR is an outcome of interplays between multiple intricate pathways responsible for the inactivation of drug and development of resistance. MDR is a major obstacle in regimens of successful application of anti-cancer therapy. An improved understanding of the molecular mechanism of multi drug resistance and cellular reprogramming can provide a promising opportunity to combat drug resistance in cancer and intensify anti-cancer therapy for the upcoming future.
Keyphrases
  • papillary thyroid
  • cancer therapy
  • multidrug resistant
  • squamous cell
  • drug delivery
  • lymph node metastasis
  • emergency department
  • childhood cancer
  • current status
  • young adults
  • drug induced