GP0.4 from bacteriophage T7: in silico characterisation of its structure and interaction with E. coli FtsZ.

Published in: BMC research notes (2016)

The mode of interaction predicted by bioinformatics techniques strongly suggests a mechanism through which GP0.4 inhibits FtsZ and further establishes the latter's druggable intrafilament interface as a potential drug target.

Keyphrases

escherichia coli
molecular docking
emergency department
risk assessment
human health
drug induced