Causal Relationship between Sex Hormone-Binding Globulin and Risk of Neuroblastoma: A Bidirectional Two-Sample Mendelian Randomization Study.

Han Wu Miao Ding Jiabei Zhu Siwei Mao Xiaochen Tang Sijia Fang Li Liu Qiuhui Pan Chao-Yan Yue

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2024)

This study highlights a novel gender-specific aspect in the risk of neuroblastoma, emphasizing the potential role of male SHBG levels in neuroblastoma incidence, and sets the stage for targeted preventative strategies and further investigation into gender-based biological mechanisms.

Keyphrases

mental health
risk factors
drug delivery
cancer therapy
transcription factor
dna binding