Methotrexate is associated with decreased total thyroxine in patients with rheumatoid arthritis.
Shu-Lin ChenQiang XuChang-Song LinPublished in: Inflammopharmacology (2023)
Methotrexate is associated with decreased TT4 levels in RA patients, and glucocorticoids is associated with decreased TT3 levels. Drugs of RA treatment may affect the thyroid function of patients while treating RA, which may be one of the causes of secondary thyroid diseases in RA patients.