BRCA1/BRCA2 germline mutations and chemotherapy-related hematological toxicity in breast cancer patients.

Alex FriedlaenderAurélie VuilleumierValeria ViassoloAurélie AymeSolène De TalhouetJean-Damien CombesJulien PeronAlexandre BodmerSophie GiraudAdrien BuissonValerie BonadonaIsabelle Gauchat-BouchardyOlivier TredanPierre O ChappuisSana Intidhar Labidi-Galy

Published in: Breast cancer research and treatment (2019)

BRCA1 germline mutations is associated with greater acute hematological toxicity in breast cancer patients. These observations could have implication for primary prophylaxis with G-CSF.

Keyphrases

breast cancer risk
dna repair
oxidative stress
liver failure
drug induced
locally advanced
squamous cell carcinoma
dna damage
intensive care unit
radiation therapy