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Sub-Inhibitory Concentrations of Ciprofloxacin Alone and Combinations with Plant-Derived Compounds against P. aeruginosa Biofilms and Their Effects on the Metabolomic Profile of P. aeruginosa Biofilms.

Didem KartTuba ReçberEmirhan NemutluMeral Sagiroglu
Published in: Antibiotics (Basel, Switzerland) (2021)
The use of curcumin, baicalein, esculetin, and cinnamaldehyde with ciprofloxacin will help fight against P. aeruginosa biofilms. To the best of our knowledge, this is the first study of its kind to define the effect of plant-based compounds as possible anti-biofilm agents with low MBICs for the treatment of P. aeruginosa biofilms through metabolomic pathways.
Keyphrases
  • candida albicans
  • pseudomonas aeruginosa
  • biofilm formation
  • healthcare
  • staphylococcus aureus
  • cystic fibrosis
  • escherichia coli
  • combination therapy
  • smoking cessation
  • replacement therapy