Protein ion yield enhancement in matrix-assisted laser desorption/ionization mass spectrometry after sample and matrix low-pressure glow discharge plasma irradiation.
Shahedeh HajianiAli Reza GhassempourBabak ShokriPublished in: Rapid communications in mass spectrometry : RCM (2021)
Low-pressure glow discharge plasma treatment greatly enhances MALDI ion signals, with a noticeable increase in incorporation, co-crystallization, protonation, and the concentration of the sample functional groups.