Therapeutic Trem2 activation ameliorates amyloid-beta deposition and improves cognition in the 5XFAD model of amyloid deposition.

Brittani R PriceTiffany L SudduthErica M WeekmanSherika JohnsonDanielle HawthorneAbigail WoolumsDonna M Wilcock

Published in: Journal of neuroinflammation (2020)

These findings indicate that Trem2 activators may be effective for the treatment of AD and possibly other neurodegenerative disorders.

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