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The validation of Short Interspersed Nuclear Elements (SINEs) as a RT-qPCR normalization strategy in a rodent model for temporal lobe epilepsy.

René A J CransJana JanssensSofie DaelemansElise WoutersRobrecht RaedtDebby Van DamPeter Paul de DeynKathleen Van CraenenbroeckChristophe Pol Stove
Published in: PloS one (2019)
In this study, we demonstrate the potential of implementing SINEs -notably the B1 element- as a stable normalization factor in a rodent model of TLE, independent of brain region or disease progression.
Keyphrases
  • temporal lobe epilepsy
  • white matter
  • quality improvement
  • risk assessment
  • human health
  • blood brain barrier