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Local selection in the presence of high levels of gene flow: Evidence of heterogeneous insecticide selection pressure across Ugandan Culex quinquefasciatus populations.

Walter Fabricio Silva MartinsCraig Stephen WildingKeith SteenHenry MawejjeTiago Rodrigues AntãoMartin James Donnelly
Published in: PLoS neglected tropical diseases (2017)
Taken together, the microsatellite and both insecticide resistance target-site markers provide evidence that in the face of intense gene flow among populations, disjunction in resistance frequencies arise due to intense local selection pressures despite an absence of insecticidal control interventions targeting Culex.
Keyphrases
  • aedes aegypti
  • zika virus
  • genome wide
  • copy number
  • genetic diversity
  • physical activity
  • drug delivery