HTLV-1 contains a high CG dinucleotide content and is susceptible to the host antiviral protein ZAP.

Paola MiyazatoMisaki MatsuoBenjy J Y TanMichiyo TokunagaHiroo KatsuyaSaiful IslamJumpei ItoYasuhiro MurakawaYorifumi Satou

Published in: Retrovirology (2019)

The post-transcriptional regulatory mechanism involving ZAP might allow HTLV-1 to maintain a delicate balance required for prolonged survival in infected individuals.

Keyphrases

transcription factor
gene expression
protein protein
free survival
amino acid
binding protein
heat shock
oxidative stress
small molecule