Drug-neutralizing Antibodies against TNF-α blockers as Biomarkers of Therapy Effect Evaluation.

Krasimir Iliev KraevMariela Geneva-PopovaVelichka PopovaStanislava PopovaAna ManevaAnastas Zgurov BatalovTeodora StankovaGinka DelchevaKatya Stefanova

Published in: Folia medica (2021)

Drug-induced neutralizing antibodies against TNF-α blockers (adalimumab and etanercept) have a negative effect on the course of inflammatory joint disease and can be used as reliable biomarker to assess the effect of the treatment with these drugs.

Keyphrases

drug induced
rheumatoid arthritis
liver injury

juvenile idiopathic arthritis
angiotensin converting enzyme
dengue virus

disease activity
mesenchymal stem cells

combination therapy
replacement therapy