Intraosseous regional prophylactic antibiotics decrease the risk of infection in total knee arthroplasty compared with intravenous antibiotics: a systematic review and meta-analysis.

Xinhuan LeiJie XiangHailan YangHongya Bao Zhong ZhuHua Luo

Published in: EFORT open reviews (2023)

IO antibiotics in TKA are safe and effective alternatives to IV antibiotics. Large randomized clinical studies comparing infection rates and related complications with IO and IV antibiotics are required.

Keyphrases

total knee arthroplasty
total hip
double blind
open label
clinical trial
risk factors
high dose
low dose
phase ii