The impact of obesity and smoking on young individuals suffering from lumbar disc herniation: a retrospective analysis of 97 cases.
Sara LenerChristoph WipplingerSebastian HartmannClaudius ThoméAnja TschuggPublished in: Neurosurgical review (2019)
The negative impact on spinal diseases may apply not only to obesity but also to smoking. To investigate the influence of obesity and smoking on the development and recovery of lumbar disc herniation in young adults. Retrospective analysis of 97 patients who presented with lumbar disc herniation at the authors' department between 2010 and 2017. Data were collected using the patients' digital health records including demographics, clinical and neurological characteristics, treatment details, and outcomes. Ninety-seven patients between 17 and 25 years were included in this retrospective analysis. Patients were categorized into two groups according to their body mass index: obese (O, ≥ 30 kg/m2) and non-obese (NO, < 30 kg/m2). The proportion of obese patients in our cohort vs. in the overall population differed significantly (19.4% vs. 3.8-7.1%, RR 3.17; p < 0.01). Group NO showed a trend toward faster recovery of motor deficits (p = 0.067) and pain (p = 0.074). Also, the proportion of regular smokers differed significantly from the numbers of known smokers of the same age (62.4% vs. 30.2%, RR 2.0; p = 0.01). Obesity plus smoking showed a significantly negative impact on motor deficits postoperatively (p = 0.015) and at discharge (p = 0.025), as well as on pain values (p = 0.037) and on analgesic consumption (p = 0.034) at 6 weeks follow-up. The negative impact of obesity and smoking on the occurrence of lumbar disc herniation could be demonstrated for individuals aged 25 or younger. Furthermore, a trend to earlier recovery of motor deficits and significantly lower pain scales for non-obese and non-smoking patients could be shown.
Keyphrases
- end stage renal disease
- weight loss
- metabolic syndrome
- type diabetes
- insulin resistance
- ejection fraction
- body mass index
- obese patients
- newly diagnosed
- chronic kidney disease
- smoking cessation
- peritoneal dialysis
- bariatric surgery
- weight gain
- adipose tissue
- traumatic brain injury
- chronic pain
- prognostic factors
- healthcare
- minimally invasive
- public health
- pain management
- neuropathic pain
- mental health
- climate change
- deep learning
- subarachnoid hemorrhage
- big data
- tertiary care
- postoperative pain
- replacement therapy