Successful haploidentical hematopoietic stem cell transplantation (HSCT) and durable engraftment by repeated donor lymphocyte infusions for a Chinese patient with transfusion-dependent hemoglobin (Hb) Hammersmith and massive splenomegaly.

Wilson Yau Ki ChanNelson C N ChanJason C C SoPamela P W LeeDaniel K L CheukS Y HaGodfrey C F ChanWing Leung

Published in: Pediatric transplantation (2022)

Allogenic haploidentical HSCT for hemoglobin Hammersmith is feasible but adequate immunosuppression during conditioning is crucial. Precise adoptive cell therapy can promote durable engraftment.

Keyphrases

cell therapy
hematopoietic stem cell
peripheral blood
stem cell transplantation
bone marrow
mesenchymal stem cells
stem cells
red blood cell
cord blood
case report
high dose
cardiac surgery
acute myeloid leukemia
low dose
acute kidney injury