Characteristics of Complement Protein Deposition in Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposition.
Meng-Yao LiuXiao-Juan YuSu-Xia WangYuan LiGuolan XingMing ChenFu-de ZhouMing-Hui ZhaoPublished in: Clinical journal of the American Society of Nephrology : CJASN (2023)
The complement system was found to be overactivated in PGNMID, and levels of urinary complements correlated with disease severity. A higher level of urinary C4d was identified as an independent risk factor for kidney failure.