The Role and Mechanism of Hyperoside against Depression-like Behavior in Mice via the NLRP1 Inflammasome.

Aoqi SongZhenghua WuWenjuan ZhaoWenqing ShiRu ChengJingjing JiangZhuojun NiHan QuXijier QiaolongbatuGuorong FanYuefen Lou

Published in: Medicina (Kaunas, Lithuania) (2022)

Hyp is one of the main active components of HP, and Hyp has antidepressant effects through the NLRP1 inflammasome, which may be connected with the CXCL1/CXCR2/BDNF signaling pathway.

Keyphrases

nlrp inflammasome
signaling pathway
major depressive disorder
depressive symptoms
pi k akt
epithelial mesenchymal transition
high fat diet induced
sleep quality
metabolic syndrome
cell migration
skeletal muscle
wild type