A Case of Parvovirus-Related Haemophagocytic Lymphohistiocytosis in a Patient with HbH Disease.
Veeraraghavan Meyyur AravamudanChaozer ErIkram HussainNicholas Wong Wai CheongChong Chern HaoNavin KuthahEmily En-Xian TanBingwen Eugene FanPublished in: Case reports in medicine (2018)
Hemophagocytic lymphohistiocytosis (HLH) is rare and life-threatening medical emergency. Parvovirus infection is rarely associated with HLH. We report a case of parvovirus-related HLH in a patient with alpha thalassaemia (HbH disease). The patient responded well to a course of dexamethasone without the need of etoposide. Based on our literature search, this is the first case of parvovirus related HLH in a patient with HbH disease in the medical literature.