The role of down staging treatment in the management of locally advanced intrahepatic cholangiocarcinoma: Review of literature and pooled analysis.
Sivesh Kathir KamarajahFrancesco GiovinazzoKeith J RobertsPankaj PuniaRobert Peter SutcliffeRavi MarudanayagamNikolaos A ChatzizachariasJohn T R IsaacDarius F MirzaPaolo MuiesanBobby Venkata DasariPublished in: Annals of hepato-biliary-pancreatic surgery (2020)
Although the evidence to support the benefits of NAT for iCCA is limited, the review supports the use of down staging treatment and also surgical resection in the cohort with response to NAT in order to improve long-term survival in patients with locally advanced iCCA.