Deposition studies of aerosol delivery by nasal cannula to infants.

Timothy E CorcoranAl SavillePhillip S AdamsDarragh J JohnstonMichael R CzachowskiYuliya A DomninaJiuann-Huey LinDaniel J WeinerAlex S HuberJoan Sanchez-de-ToledoCecilia W Lo

Published in: Pediatric pulmonology (2019)

With the delivery system used here, pulmonary aerosol delivery via nasal cannula was very inefficient at the flow rates required to provide oxygen support. Even at low flows, nasal deposition was substantial and local toxicity must be considered.

Keyphrases

chronic rhinosinusitis
extracorporeal membrane oxygenation
respiratory failure
positive airway pressure
pulmonary hypertension
oxidative stress
water soluble
obstructive sleep apnea
sleep apnea
oxide nanoparticles