ADAM10-Mediated Ectodomain Shedding Is an Essential Driver of Podocyte Damage.

Marlies SachsSebastian WetzelJulia ReicheltWiebke SachsLisa SchebsdatStephanie ZielinskiLisa SeipoldLukas HeintzStephan A MüllerOliver KretzMaja LindenmeyerThorsten WiechTobias B HuberRenate Lüllmann-RauchStefan F LichtenthalerPaul SaftigCatherine Meyer-Schwesinger

Published in: Journal of the American Society of Nephrology : JASN (2021)

ADAM10-mediated ectodomain shedding of injury-related cadherins drives podocyte injury.

Keyphrases

diabetic nephropathy
high glucose
oxidative stress
endothelial cells