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Protocol for psychometric evaluation of the Amyotrophic Lateral Sclerosis - Bulbar Dysfunction Index (ALS-BDI): a prospective longitudinal study.

Yana YunusovaAshley WaitoCarolina BarnettAnna HuynhRosemary MartinoAgessandro AbrahaoGary L PatteeJames D BerryLorne ZinmanJordan R Green
Published in: BMJ open (2022)
This study has been reviewed and approved by research ethics boards at two data collection sites: Sunnybrook Health Science Centre, primary (Toronto, Canada; ID3080) and Mass General Brigham (#2013P001746, Boston, USA). Prior to participation in the study, the participants sign the informed consent in accordance with the Declaration of Helsinki. Once validated, the ALS-BDI will be disseminated to key stakeholders. Following validation, the ALS-BDI and any required training material will be implemented for clinical use in a context of a multidisciplinary ALS clinic and used as an outcome measure for clinical trials in ALS research.
Keyphrases
  • amyotrophic lateral sclerosis
  • public health
  • clinical trial
  • healthcare
  • physical activity
  • mental health
  • big data
  • primary care
  • oxidative stress
  • climate change
  • artificial intelligence
  • phase ii
  • phase iii