Enrichment of Motilin Receptor Loss-of-Function Variants in Gastroparesis.

Christos M PolymeropoulosJesse L CarlinChangfu XiaoGunther BirznieksChristos M PolymeropoulosMihael H Polymeropoulos

Published in: Clinical and translational gastroenterology (2022)

Motilin receptor is an important therapeutic target for the treatment of hypomotility disorders. The identified genetic variants may be important risk factors for disease as well as may inform treatments, especially those targeting motilin receptor.

Keyphrases

binding protein
gene expression
copy number
dna methylation