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DISCO is key to successful centriole maturation.

Noémie GaudinPaula Martin GilJuliette Azimzadeh
Published in: The Journal of cell biology (2021)
Centriole maturation is essential for ciliogenesis, but which proteins and how they regulate ciliary assembly is unclear. In this issue, Kumar et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202011133) shed light on this process by identifying a ciliopathy complex at the distal mother centriole that restrains centriole length and supports the formation of distal appendages.
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